上图反应条件：(A) Screening of the activator and reductant for the nitromethane activation. Reaction conditions: S1 (0.3 mmol), MeNO2 (1.2 mmol), activator (0.6 mmol), reductant (0.75 mmol) in AcOH (0.5 mL) at 100°C for 12 hours under air. The yield of amides in parentheses was determined by 1H NMR analysis. For details, see supplementary materials: (B) Substrate scope of ketones. (C) Substrate scope of aldehydes. For details, see supplementary materials. * MeNO2 (9.0 mmol) was used.

上图反应条件：

(A) Substrate scope of alkynes. (B) Nitrogenation of simple alkylarenes: Conditions C: ethylbenzene (0.3  mmol), Co(OAc)2•4H2O (0.015 mmol), NHydroxyphthalimide (0.03 mmol) in AcOH (0.5 mL) were stirred at 80°C for 12 hours under 1atm O2, then MeNO2  (9.0 mmol), Tf2O (0.6 mmol), HCOOH (0.75 mmol) were added and stirred at 100°C 

for 12 hours under air. Conditions D: methylbenzene (0.3 mmol), Co(OAc)2•4H2O (0.006 mmol), N-Hydroxyphthalimide (0.03 mmol) in Hexafluoroisopropanol (0.6 mL) were stirred at room temperature for 12 hours under 1 atm O2, then MeNO2 (9.0 mmol), Tf2O (0.6 mmol), HCOOH (0.75 mmol), AcOH (0.5 mL) were added and stirred at 100°C for 12 hours under air. (C) The latestage modification of drugs or bioactive molecules. (D) Gramscale reaction with cumene and cyclohexylbenzene. (E)  ε-Caprolactam (CPL) and macrocyclic lactam synthesis from cyclic ketones.on D